The green-lipped mussel is a nutritional supplement taken from a type of mussel native to New Zealand. It can be taken in tablet form or as a gel aplication.
It contains omega-3 fatty acids, which have anti-inflammatory and joint-protecting properties.
A small trial at the University of Queensland found high doses (3,000mg per day) produced significant improvement in levels of joint pain, stiffness and mobility after only eight weeks when taken with paracetamol or NSAIDs. The results and variables of the trial were of low quality so must be taken with caution.
Reported side effects of the green lipped mussels occassionally include gastrointestinal discomfort. Interactions with other drugs haven’t been well studied, but it is recommended that care should be taken with anticoagulant medication.